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Vitamin K2 MK-7 45mcg Low-Dose Softgels – Bone & Heart | Life Extension

Vitamin K2 MK-7 45mcg Low-Dose Softgels – Bone & Heart | Life Extension

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Life Extension Low-Dose Vitamin K2 MK-7 (45 mcg) – Slow-Release Menaquinone-7 for Bone Density, Arterial Protection & Calcium Routing

Vitamin K2 as MK-7 (menaquinone-7) is the long-acting, slow-metabolizing form of vitamin K2 — and the form best suited for consistent, sustained activity throughout the day. Unlike MK-4, which clears the bloodstream within hours, MK-7 has a half-life of approximately 72 hours, providing a steady supply of active K2 to activate the proteins that direct calcium where it belongs: into bones and away from arteries. At 45 mcg, this low-dose formula is ideal for those pairing K2 with a vitamin D3 supplement, a multivitamin, or a D3+K2 combination product — or for those who want precise, conservative K2 dosing under practitioner guidance.


Key Benefits

  • MK-7 — the long-acting form of vitamin K2 — menaquinone-7 has a ~72-hour half-life vs. MK-4’s ~1-hour half-life; provides sustained, consistent K2 activity throughout the day from a single daily softgel
  • Activates osteocalcin for bone matrix calcium binding — K2 carboxylates osteocalcin, the protein that anchors calcium into bone; without adequate K2, calcium absorbed via vitamin D cannot be properly incorporated into bone
  • Activates Matrix Gla Protein (MGP) to protect arteries — MGP is the body’s primary inhibitor of arterial and soft tissue calcification; K2 is required to activate it; low K2 = inactive MGP = calcium depositing in arteries
  • Routes calcium to bones, away from arteries — the core mechanism of K2: ensures calcium absorbed from diet and supplements ends up in the skeletal system, not in vascular or soft tissue
  • Low-dose 45 mcg — ideal for stacking and precision dosing — pairs cleanly with vitamin D3 supplements, multivitamins, or D3+K2 combination products; allows fine-tuned K2 intake without over-supplementing
  • Trans-MK-7 — the biologically active isomer — Life Extension uses trans-menaquinone-7, the naturally occurring, biologically active form; some cheaper products use cis-MK-7, which has negligible activity
  • MCT oil base for fat-soluble absorption — K2 is fat-soluble; the MCT carrier ensures consistent absorption even without a full meal
  • 90 softgels — a 3-month supply at one daily — excellent value for a daily foundational supplement

Who It’s For

  • Those taking vitamin D3 without K2 — vitamin D3 increases calcium absorption; without K2, that calcium has no guidance system; adding MK-7 completes the D3+K2 synergy for bone and arterial health
  • Bone health and osteoporosis prevention — K2 is essential for osteocalcin activation and calcium incorporation into bone matrix; a foundational addition to any bone health protocol alongside D3, calcium, and magnesium
  • Cardiovascular and arterial protection — MK-7 activates MGP to inhibit arterial calcification; important for long-term vascular health, especially for those with cardiovascular risk factors
  • HTMA protocol users — calcium metabolism and routing are central to HTMA mineral balancing; K2 ensures calcium absorbed via D3 is directed to the skeletal system rather than soft tissue
  • Those who prefer low-dose, stackable K2 — 45 mcg allows precise control when combining with a multivitamin or D3+K2 product that already contains some K2
  • Practitioners and their patients — the low-dose MK-7 format gives practitioners flexibility to titrate K2 intake precisely based on individual patient needs and lab findings
  • Those on anticoagulant therapy — consult your physician first — vitamin K2 may interact with warfarin (Coumadin) and related medications; not suitable without medical supervision

Supplement Facts

Serving Size: 1 Softgel
Servings Per Container: 90
Suggested Use: Take one (1) softgel daily with food, or as recommended by your healthcare practitioner.

Ingredient Amount Per Serving
Vitamin K2 (as trans-menaquinone-7 / MK-7) 45 mcg

Other Ingredients: Medium chain triglycerides, gelatin, glycerin, purified water, carob color.


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⚠️ Caution

If you are taking warfarin (Coumadin) or related anticoagulant medications, consult your healthcare provider before taking this product — vitamin K2 may interfere with anticoagulant therapy. Consult your healthcare professional before use if pregnant or lactating. Do not use if outer seal is broken or damaged. Keep out of the reach of children.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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