Sacro-B™ Probiotic by Thorne – S. Boulardii 5B CFU | 60 Caps

⚠️ Currently Out of Stock: You can order this product through our Fullscript^® dispensary and receive 15% off your first order.

Sacro-B™ by Thorne® delivers a minimum of 5 billion CFU of Saccharomyces boulardii per delayed-release capsule — a clinically studied probiotic yeast that supports gastrointestinal immune defense, beneficial flora, and digestive comfort.* In clinical studies, S. boulardii has demonstrated the ability to increase production of secretory IgA (sIgA) — the first-line defense immunoglobulin of the GI tract — making it one of the most well-researched gut immune support supplements available.*

Key Benefits

• ✅ Secretory IgA (sIgA) support — clinically shown to increase sIgA, the GI tract’s primary immune defense immunoglobulin*
• ✅ Beneficial flora support — supports the growth of healthy intestinal microflora*
• ✅ Occasional diarrhea relief — clinically studied for mitigating occasional diarrhea*
• ✅ Delayed-release capsule — protects S. boulardii through stomach acid for delivery to the intestinal tract
• ✅ 5 billion CFU minimum per capsule — guaranteed potency at time of use
• ✅ Flexible dosing — 1 capsule one to three times daily between meals
• ✅ 60 capsules per bottle — 20–60 day supply depending on dose

Who It’s For

• Those following GI-MAP or HTMA protocols where gut immune support or microbiome restoration is recommended*
• Anyone experiencing occasional diarrhea or digestive disruption*
• Those recovering from antibiotic use who want to restore beneficial gut flora*
• Anyone seeking clinically studied gut immune support via secretory IgA enhancement*
• Those wanting a practitioner-trusted, pharmaceutical-grade probiotic yeast from Thorne

Why Saccharomyces boulardii?

S. boulardii is a non-pathogenic yeast probiotic — distinct from bacterial probiotics — that is naturally resistant to antibiotics, making it effective even when taken alongside antibiotic therapy.* Its primary mechanism is enhancing secretory IgA production in the gut, which strengthens the mucosal immune barrier and supports a balanced intestinal environment.* Thorne’s Sacro-B™ uses a delayed-release capsule to ensure the yeast survives stomach acid and reaches the intestinal tract intact.

Supplement Facts

Serving Size: 1 Capsule  |  Servings per Container: 60

Per Serving:

• Saccharomyces boulardii — 250mg (minimum 5 billion CFU)

Other Ingredients: Calcium laurate, delayed-release capsule, medium chain triglycerides, rice bran.

Suggested Use

Take 1 capsule one to three times daily between meals, or as recommended by your healthcare professional.

Warning: Contains a yeast-derived ingredient — contraindicated in individuals with a history of hypersensitivity to yeast or any other ingredient. If pregnant, consult your healthcare professional before use. Keep out of reach of children.

Sacro-B™ — 60 Delayed-Release Capsules — 5B CFU S. boulardii — by Thorne®