DMSA is an abbreviation for 2, 3-Dimercaptosuccinic Acid. It is also marketed under the trade names of Chemet and Succimer. It is an FDA-approved drug for treatment of lead toxicity in children. DMSA chelation therapy is also an effective oral chelating agent for removing mercury from the body.
DMSA heavy metal chelation is taken orally (by mouth), and the usual adult dosage for mercury removal is 500 mg (five 100 mg capsules) first thing in the morning on an empty stomach. This dosage is taken three days a week for three months until a urine provocation challenge is performed to measure mercury levels. If there is still a load of mercury, then another round of DMSA is given.
The main downside to DMSA oral chelation for both adults and kids is that, because it works in the bloodstream, a high dosage has to be given for it to be effective. This can create two problems. Firstly, there may be a “retracing” or toxic crisis – the DMSA unbinds heavy metals from the tissue faster than the organs of elimination can excrete it from the body. If this happens then the body redistributes the metals into different tissue.
Secondly, the higher the dosage of the chelating agent, the more likely there will be a depletion of essential minerals like magnesium and calcium because chelating agents like DMSA also chelate minerals. It is vital – especially for children – that the amounts of DMSA be monitored on each individual child to make sure that metals are excreted safely and not just re-sequestered into different tissues. It is also vital to implement a good essential mineral formula to replenish what might be depleted in doing this heavy metal chelation.
Common side-effects of DMSA heavy metal chelation include: diarrhea, nausea, vomiting, appetite loss and rashes. As with other chelating drugs, kidney and liver function needs to be closely monitored.
We feel there is a better, safer alternative for both children and adults. Firstly, there is the EBN® Detoxifying Clay Baths and the Kids Clear™ Detoxifying Clay Baths. These are pharmaceutical-grade,
sodium bentonite clays. When mixed in warm to hot bathwater or a foot soak the bentonite will create a negative electrical charge in the water. This negative ionic charge attracts and helps to pull out, though the open pores of the skin, all the positively-charged toxins, like mercury and lead, from the bloodstream and surface tissue.
This can be safer and more preferable than DMSA chelation because most of the toxins are secreted molecularly through the body’s largest organ, the skin. This alleviates the burden that is placed on the kidneys and liver, so there is less chance of a redistribution of these contaminants if used properly.
Secondly, we offer the Bio-Chelat™ and Kids Chelat™ (liquid) heavy metal chelators. These are proprietary German formulas that work in the gut or small intestine, not the bloodstream. As a consequence, they need only a fraction of their chelating agent, EDTA, which is a synthetic amino acid. In fact, in a full bottle (which lasts one month for an adult and two months for a child) there is only 240 mg of EDTA, as compared to 500 mg per day of oral DMSA!
In the clinical study performed on this formula in Germany, it was shown that this chelation liquid was both safe and effective for infants, children and adults for sub-acute and chronic heavy metal toxicity. It was also shown that this formula decreased the toxic burden of all metals – including lead and mercury -- without depleting essential minerals like ordinary oral chelators are prone to do. |